ASSOCIATION OF OBESITY AND SEVERE OUTCOMES OF COVID-19 IN A YOUNGER POPULATION OF ADULT PATIENTS (18-60 YEARS OLD) ADMITTED IN A TERTIARY HOSPITAL

  • Donnah Bless Mosqueda SPMC

Abstract

  1. Objective : 

To describe the association of obesity and the  coronavirus disease 2019 (COVID-19)  severe outcomes, among the younger adult patients, 18 to 60 years of age. Severe outcomes include high flow oxygen requirement, intensive care unit (ICU) admission, mechanical ventilation(MV) and death. 

Methodology 

This is a single center analytical retrospective study, conducted on patients who were admitted with laboratory confirmed diagnosis of  COVID-19. For the classification of our cohort, we have defined obesity, based on World Health Organization (WHO) criteria, as Body Mass Index (BMI) greater than or equal to 30 kg/m2. We used this cut-off and dichotomized our patients accordingly.  Patients were grouped by age: younger adults 18-60 years old and those who are older > 60 years old. Severe clinical outcomes were then compared among the groups. 

Results 

A total of 391 patients ( 55% male, with a mean age 52.7 ) were included, and 26.3 % were obese. Results show that there is an association between increased BMI and severe outcomes. Increased BMI ( ≥ 30)  was significantly associated with high flow oxygen supplementation (OR=1.696 , 95% CI 1.039-2.774, P=0.035) and mechanical ventilation (OR=1.823, 95% CI 1.056-3.150,P=0.031).  Younger adults who are obese, compared to non-obese,  have about 2x the risk of requiring high flow oxygen, ICU admission and MV. The risk for mortality is lesser for  these younger obese patients, however the result is not statistically significant (OR = 0.505, 95% CI 0.102-2.493,P= 0.402).  

 

Conclusion 

Higher BMI ≥ 30 kg/m2  was associated with severe COVID-19 outcomes, except mortality, among younger adult population in the inpatient setting. 

Published
2024-01-31
How to Cite
Mosqueda, D. B. (2024). ASSOCIATION OF OBESITY AND SEVERE OUTCOMES OF COVID-19 IN A YOUNGER POPULATION OF ADULT PATIENTS (18-60 YEARS OLD) ADMITTED IN A TERTIARY HOSPITAL. Southern Philippines Medical Center Journal of Health Care Services, 10(1). Retrieved from https://submissions.spmcjournal.com/index.php/SPMCJHCS/article/view/51
Issue
Vol 10 No 1 (2024)
Section
Research

Copyright (c) 2024 Donnah Bless Mosqueda

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