https://submissions.spmcjournal.com/index.php/SPMCJHCS The Official Journal of Southern Philippines Medical Center Southern Philippines Medical Center en-US Southern Philippines Medical Center Journal of Health Care Services 2467-5962 <p>Authors who publish with this journal agree to the following terms:</p> <ol> <li>Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a <a href="http://creativecommons.org/licenses/by-nc/4.0/" rel="license">Creative Commons Attribution-NonCommercial 4.0 International License</a> that allows others to share the work for non-commercial purposes with an acknowledgement of the work's authorship and initial publication in this journal.</li> <li>Authors are able to enter into separate, additional, non-commercial contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.</li> <li>Authors grant the journal permission to rewrite, edit, modify, store and/or publish the submission in any medium or format a version or abstract forming part thereof, all associated supplemental materials, and subsequent errata, if necessary, in a publicly available publication or database.</li> <li>Authors warrant that the submission is original with the authors and does not infringe or transfer any copyright or violate any other right of any third parties.</li> </ol> https://submissions.spmcjournal.com/index.php/SPMCJHCS/article/view/81 <p>Toxic epidermal necrolysis (TEN) is a rare and severe dermatological emergency characterized by extensive necrosis and detachment of the epidermis, leading to significant mucous membrane erosions and severe systemic symptoms. While specific classes of conventional pharmaceuticals are identified as the primary cause of TEN, recent reports have implicated herbal medications as triggers. This case highlights a 48-year-old Filipino woman with invasive cervical cancer who developed TEN following the use of an herbal medication containing 23 botanical extracts. Despite immediate discontinuation of the herbal medication, the patient experienced rapid progression of vesicles and bullae to widespread epidermal detachment involving 90% of the body surface area. Histopathological examination confirmed the diagnosis of TEN. The patient was treated with systemic corticosteroids and supportive care, leading to a full recovery within 14 days. This case underscores the need for enhanced awareness among healthcare providers regarding the potential severe adverse drug reactions associated with herbal medicines and the necessity for stringent regulatory measures to ensure their safety. Moreover, underreporting of adverse events by both patients and healthcare professionals is due to a significant lack of awareness about the potential safety issues linked to herbal use. Therefore, enhanced education and strengthened regulatory policies are imperative to safeguard public health as the global use of herbal remedies and their associated adverse effects continue to rise.</p> Nadra Magtulis Mary Jo Kristine Bunagan Copyright (c) 2024 Nadra Magtulis, Mary Jo Kristine Bunagan https://creativecommons.org/licenses/by-nc/4.0 2024-12-13 2024-12-13 10 2